Details of the Drug

General Information of Drug (ID: DM1WEHC)

Drug Name
Buparlisib
Synonyms BKM120
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Phase 3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 410.4
Logarithm of the Partition Coefficient (xlogp) 1.5
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 11
Chemical Identifiers
Formula
C18H21F3N6O2
IUPAC Name
5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine
Canonical SMILES
C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4
InChI
InChI=1S/C18H21F3N6O2/c19-18(20,21)13-9-15(22)23-11-12(13)14-10-16(26-1-5-28-6-2-26)25-17(24-14)27-3-7-29-8-4-27/h9-11H,1-8H2,(H2,22,23)
InChIKey
CWHUFRVAEUJCEF-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
16654980
ChEBI ID
CHEBI:71954
CAS Number
944396-07-0
UNII
0ZM2Z182GD
DrugBank ID
DB11666
TTD ID
D01QSO
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PI3-kinase alpha (PIK3CA) TTEUNMR PK3CA_HUMAN Inhibitor [2]
PI3-kinase beta (PIK3CB) TTTHBCA PK3CB_HUMAN Inhibitor [2]
PI3-kinase delta (PIK3CD) TTGBPJE PK3CD_HUMAN Inhibitor [2]
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [4]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Gene/Protein Processing [3]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [3]
E3 ubiquitin-protein ligase XIAP OT24GP9B XIAP_HUMAN Gene/Protein Processing [3]
Forkhead box protein O3 (FOXO3) OTHXQG4P FOXO3_HUMAN Gene/Protein Processing [4]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Gene/Protein Processing [3]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Post-Translational Modifications [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Breast cancer
ICD Disease Classification 2C60-2C65
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase gamma (PIK3CG) DTT PIK3CG 1.98E-01 -0.05 -0.55
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 1.8011 3.7832 1.5167 16.7997
EW-7 GDSC2 -0.2215 2.389 -0.3362 36.0948
EW-12 GDSC2 -0.2102 3.6822 -0.6369 37.2502
EW-1 GDSC2 -0.1822 2.3382 -0.2855 35.6533
ES1 GDSC2 -0.1554 2.8487 -0.355 35.8145
ES5 GDSC2 0.0661 3.0142 -0.1522 33.7223
ES8 GDSC2 0.0865 2.2529 0.0151 32.8216
HuO9 GDSC2 0.2733 3.2466 0.0152 31.8685
ES7 GDSC2 0.3345 2.5341 0.238 30.4657
EW-11 GDSC2 0.3809 4.446 -0.2522 32.5485
A-673 GDSC2 0.4752 1.728 0.4675 28.6064
SK-ES-1 GDSC2 0.5188 2.967 0.3519 28.98
EW-18 GDSC2 0.5874 2.9227 0.4364 28.2139
MG-63 GDSC2 0.6634 3.9099 0.2411 28.8431
SK-PN-DW GDSC2 0.6887 2.4967 0.6242 26.7532
CHSA8926 GDSC2 0.7439 5.4658 -0.2697 30.8683
EW-22 GDSC2 0.8332 4.0365 0.3819 27.3273
SJSA-1 GDSC2 0.8488 3.6849 0.5157 26.5582
TC-71 GDSC2 0.8622 2.4891 0.8107 24.9462
G-292 clone A141B1 GDSC2 0.8783 4.7278 0.1728 28.1771
NY GDSC2 0.9397 4.5204 0.3189 27.1606
HOS GDSC2 1.0083 2.4389 0.972 23.4019
CADO-ES1 GDSC2 1.038 2.398 1.0079 23.0724
EW-3 GDSC2 1.1478 3.927 0.7602 23.8842
MHH-ES-1 GDSC2 1.1575 3.4202 0.9322 22.9071
EW-24 GDSC2 1.172 6.83 -0.4368 29.6744
CAL-78 GDSC2 1.3532 4.3453 0.8274 22.6092
NOS-1 [Human HNSCC] GDSC2 1.3585 6.634 -0.1607 27.6671
EW-16 GDSC2 1.434 5.054 0.6231 23.3876
CAL-72 GDSC2 1.4826 5.429 0.5104 23.7939
ES6 GDSC2 1.635 7.4974 -0.2969 27.1628
ES4 GDSC2 1.6725 7.3112 -0.1718 26.4454
SaOS-2 GDSC2 1.9086 5.5957 0.8659 20.1122
CHSA0011 GDSC2 2.0493 3.9243 1.7321 14.5089
HuO-3N1 GDSC2 2.1013 7.5467 0.1225 23.39
U2OS GDSC2 2.265 5.513 1.2565 16.4777
CHSA0108 GDSC2 2.4534 5.6913 1.3535 15.2108
H-EMC-SS GDSC2 2.5024 7.3686 0.5807 19.5407
EW-13 GDSC2 3.3501 9.0457 0.4835 17.3443
U-CH2 GDSC2 3.4909 6.2203 2.011 7.8178
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 162 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 1.6942 3.2068 1.5756 16.9546
RPMI-8402 GDSC2 -1.8293 0.998 -1.8755 51.6239
NCI-H929 GDSC2 -1.7858 0.5802 -1.8044 51.232
AMO1 GDSC2 -1.1454 0.6364 -1.152 44.854
SUP-B8 GDSC2 -1.0906 1.9808 -1.2049 44.6036
HAL-01 GDSC2 -0.9917 1.9214 -1.0904 43.6059
A4/Fukuda GDSC2 -0.9434 1.8731 -1.0322 43.1062
L-363 GDSC2 -0.94 2.3082 -1.0969 43.2672
Jurkat GDSC2 -0.9126 1.195 -0.9355 42.5849
IM-9 GDSC2 -0.9036 0.1865 -0.9038 42.4041
P32/ISH GDSC2 -0.862 0.476 -0.8633 41.9921
SR GDSC2 -0.8453 0.8543 -0.8523 41.8493
KY821 GDSC2 -0.7668 3.1179 -1.0862 42.078
SU-DHL-5 GDSC2 -0.7147 0.6691 -0.7168 40.5179
JVM-3 GDSC2 -0.7092 1.1083 -0.7217 40.5096
MOLM-16 GDSC2 -0.6789 0.2187 -0.679 40.1491
GDM-1 GDSC2 -0.652 1.9532 -0.7323 40.2125
NB4 GDSC2 -0.5953 1.0451 -0.6031 39.3471
ATN-1 GDSC2 -0.5502 1.0322 -0.5568 38.8887
DEL GDSC2 -0.5377 1.421 -0.5608 38.8389
KMS-12-BM GDSC2 -0.4494 1.8184 -0.5015 38.0852
JVM-2 GDSC2 -0.436 3.1093 -0.7232 38.8745
H9 GDSC2 -0.4356 1.9375 -0.5003 38.0021
VAL GDSC2 -0.43 1.9832 -0.4999 37.9686
Mono-Mac-6 GDSC2 -0.4248 1.4764 -0.4473 37.706
RCH-ACV GDSC2 -0.363 1.3578 -0.377 37.0465
MOLM-13 GDSC2 -0.3316 2.6421 -0.5024 37.4203
697 GDSC2 -0.31 1.8873 -0.3616 36.691
BC-1 GDSC2 -0.3081 0.9894 -0.3106 36.4399
ALL-SIL GDSC2 -0.2881 2.2407 -0.3839 36.6715
SUP-M2 GDSC2 -0.2668 0.7226 -0.2671 36.0144
VL51 GDSC2 -0.1923 2.912 -0.4096 36.2511
ARH-77 GDSC2 -0.1839 2.0418 -0.2456 35.4784
SU-DHL-6 GDSC2 -0.1387 2.1727 -0.2143 35.092
CRO-AP2 GDSC2 -0.1187 1.5271 -0.1337 34.601
OCI-Ly7 GDSC2 -0.1127 1.934 -0.1582 34.6898
Karpas-45 GDSC2 -0.1016 1.8318 -0.1368 34.5289
KMS-11 GDSC2 -0.0913 2.8193 -0.2788 35.1318
Kasumi-1 GDSC2 -0.0782 1.4921 -0.0904 34.1814
Jiyoye GDSC2 -0.0542 1.8031 -0.0848 34.0309
ALL-PO GDSC2 -0.0513 2.2494 -0.1317 34.2421
Farage GDSC2 -0.038 1.5175 -0.0502 33.7781
JSC-1 GDSC2 -0.0354 1.6507 -0.0544 33.7857
CTV-1 GDSC2 -0.0167 1.7571 -0.0422 33.6302
YT GDSC2 0.0032 1.4331 -0.0047 33.3431
SU-DHL-16 GDSC2 0.0161 2.39 -0.0808 33.6485
NK-92MI GDSC2 0.0261 2.1889 -0.0408 33.4039
WSU-DLCL2 GDSC2 0.0288 1.2291 0.0262 33.0602
KM-H2 GDSC2 0.0357 1.8915 0.0019 33.1456
MM1.S GDSC2 0.0396 2.3106 -0.0433 33.3466
KE-37 GDSC2 0.0648 1.6166 0.0509 32.7553
NALM-6 GDSC2 0.0674 2.7889 -0.0998 33.4716
GA-10 GDSC2 0.0697 1.7494 0.0483 32.7438
DoHH2 GDSC2 0.0706 1.3354 0.0666 32.6475
OCI-M1 GDSC2 0.0708 2.2553 -0.002 32.9854
BV-173 GDSC2 0.1081 3.6717 -0.2868 34.1013
JeKo-1 GDSC2 0.1691 2.8611 -0.0048 32.4952
BONNA-12 GDSC2 0.1704 2.0936 0.1238 31.8594
GR-ST GDSC2 0.2057 3.7644 -0.2093 33.2515
MLMA GDSC2 0.2174 3.5566 -0.133 32.8476
QIMR-WIL GDSC2 0.2651 1.6449 0.2555 30.724
A3/Kawakami GDSC2 0.2669 2.0016 0.2346 30.8197
OCI-AML-3 GDSC2 0.2805 4.5106 -0.3838 33.6177
BE-13 GDSC2 0.2832 4.2942 -0.3028 33.2613
HC-1 GDSC2 0.3061 2.1443 0.2618 30.4871
RPMI-6666 GDSC2 0.3129 2.5409 0.2137 30.695
CTB-1 GDSC2 0.3241 2.324 0.2589 30.4126
ML-2 GDSC2 0.3395 1.6985 0.3296 29.9786
CESS GDSC2 0.3515 2.381 0.2802 30.1687
MHH-PREB-1 GDSC2 0.3526 2.1881 0.3061 30.0322
BC-3 GDSC2 0.3553 1.7287 0.3445 29.8251
HDLM-2 GDSC2 0.3659 3.6012 0.0156 31.4002
Namalwa GDSC2 0.3816 2.7046 0.2581 30.1304
DB GDSC2 0.3824 3.4844 0.0682 31.065
U-698-M GDSC2 0.3882 1.4689 0.3857 29.453
SKM-1 GDSC2 0.4075 1.954 0.3855 29.3573
Loucy GDSC2 0.4134 2.494 0.3295 29.6122
BALL-1 GDSC2 0.4154 1.9172 0.3962 29.2637
OCI-AML-2 GDSC2 0.4267 2.8148 0.2849 29.7726
KOPN-8 GDSC2 0.4476 1.9002 0.4308 28.9288
HL-60 GDSC2 0.4513 2.3586 0.3899 29.1178
JJN-3 GDSC2 0.4532 2.2475 0.4059 29.027
SU-DHL-1 GDSC2 0.4543 3.0536 0.2614 29.7546
MC116 GDSC2 0.4575 1.7529 0.4484 28.7905
Karpas-299 GDSC2 0.4617 3.3759 0.1856 30.0972
MOLP-8 GDSC2 0.4717 3.2765 0.2237 29.8585
TUR GDSC2 0.4807 1.509 0.4785 28.5229
EoL-1 GDSC2 0.4878 2.2722 0.4397 28.684
KMOE-2 GDSC2 0.4968 4.5736 -0.175 31.6317
LAMA-84 GDSC2 0.5001 3.6532 0.1459 30.1047
KCL-22 GDSC2 0.502 1.8955 0.4873 28.3726
THP-1 GDSC2 0.5108 2.7696 0.3853 28.8491
RS4;11 GDSC2 0.5191 3.9044 0.0864 30.3024
P12-Ichikawa GDSC2 0.5199 4.7219 -0.2065 31.6594
ST486 GDSC2 0.5327 1.7307 0.5262 28.0229
WSU-NHL GDSC2 0.5415 1.7351 0.5351 27.9339
L-428 GDSC2 0.549 2.6716 0.4453 28.3552
HT GDSC2 0.5559 2.9263 0.4013 28.547
Karpas-1106P GDSC2 0.5611 2.8035 0.433 28.3597
P31/FUJ GDSC2 0.5761 1.6831 0.5718 27.5762
NU-DUL-1 GDSC2 0.5775 1.6498 0.574 27.5584
MV4-11 GDSC2 0.5867 1.6122 0.584 27.462
OCI-Ly19 GDSC2 0.6087 1.7909 0.6018 27.2622
TALL-1 [Human adult T-ALL] GDSC2 0.6383 3.6361 0.3017 28.6575
MOLT-13 GDSC2 0.6521 1.7196 0.6482 26.8117
RL GDSC2 0.6551 2.1116 0.6318 26.8795
NKM-1 GDSC2 0.6572 1.8134 0.6506 26.774
Karpas-620 GDSC2 0.6771 4.316 0.114 29.407
EB2 GDSC2 0.6816 6.2178 -0.6574 32.7519
CCRF-CEM GDSC2 0.7189 1.6589 0.717 26.1313
KG-1 GDSC2 0.7213 3.6464 0.389 27.8158
SUP-T1 GDSC2 0.7289 3.4181 0.4652 27.3856
MOLT-4 GDSC2 0.7297 1.8608 0.723 26.0471
PF-382 GDSC2 0.7477 4.6266 0.0732 29.2712
LC4-1 GDSC2 0.7539 3.7025 0.4069 27.5691
MOLT-16 GDSC2 0.7574 1.4742 0.7572 25.7363
CA46 GDSC2 0.7689 3.2439 0.5566 26.7196
Karpas-422 GDSC2 0.7725 5.1152 -0.0945 29.9472
OPM-2 GDSC2 0.8107 1.9528 0.8025 25.2417
DG-75 GDSC2 0.8135 2.6557 0.7333 25.5833
SIG-M5 GDSC2 0.8324 1.441 0.8323 24.9833
SUP-HD1 GDSC2 0.8392 3.5016 0.5613 26.363
Raji GDSC2 0.8412 2.4208 0.797 25.1196
RPMI-8226 GDSC2 0.8532 2.2591 0.8267 24.9083
MEG-01 GDSC2 0.8695 2.8265 0.7627 25.1607
BL-41 GDSC2 0.8732 1.5371 0.873 24.574
MHH-CALL-2 GDSC2 0.8851 3.0057 0.7418 25.1957
Ku812 GDSC2 0.9148 3.3926 0.6753 25.4075
Hs 445 GDSC2 0.9315 4.3575 0.3719 26.9252
WIL2 NS GDSC2 0.9795 3.2087 0.7955 24.4659
P30/OHK GDSC2 1.0035 3.6065 0.7087 24.8182
SU-DHL-10 GDSC2 1.0225 1.538 1.0225 23.0752
MY-M12 GDSC2 1.0497 4.5889 0.4095 26.1956
Reh GDSC2 1.1 3.4856 0.8504 23.6129
PL-21 GDSC2 1.1243 2.3269 1.1049 22.1511
RC-K8 GDSC2 1.1329 4.7091 0.4502 25.612
L-540 GDSC2 1.1384 3.2753 0.9516 22.891
SCC-3 GDSC2 1.1571 2.0753 1.1524 21.7479
Ramos.2G6.4C10 GDSC2 1.1726 1.9471 1.1711 21.5762
NOMO-1 GDSC2 1.1902 2.3218 1.1741 21.4734
SUP-B15 GDSC2 1.2106 4.023 0.7944 23.4167
HEL GDSC2 1.2117 5.4625 0.2174 26.4675
LP-1 GDSC2 1.213 2.5404 1.1772 21.3454
SU-DHL-4 GDSC2 1.2991 2.2305 1.292 20.3352
Karpas-231 GDSC2 1.3498 2.6328 1.3112 19.9875
K-562 GDSC2 1.3677 5.1665 0.5062 24.2984
MHH-CALL-4 GDSC2 1.373 4.4398 0.8117 22.6101
CML-T1 GDSC2 1.3954 3.057 1.2854 19.9045
Daudi GDSC2 1.4765 3.5774 1.2328 19.8173
L-1236 GDSC2 1.4805 4.4794 0.91 21.6024
DND-41 GDSC2 1.5386 4.6124 0.9174 21.3155
EM-2 GDSC2 1.5848 4.8709 0.8578 21.4577
MN-60 GDSC2 1.5968 5.6544 0.526 23.2402
Granta-519 GDSC2 1.606 4.6313 0.9804 20.6777
U266B1 GDSC2 1.7775 6.3315 0.394 23.223
TK [Human B-cell lymphoma] GDSC2 1.9381 4.7315 1.2836 17.5741
EJM GDSC2 2.4829 5.5239 1.4621 14.4462
HH [Human lymphoma] GDSC2 2.7317 5.6389 1.6411 12.4814
ROS-50 GDSC2 2.8281 7.0521 1.0308 15.8693
SK-MM-2 GDSC2 3.033 7.6778 0.8988 15.986
SU-DHL-8 GDSC2 3.1099 5.6246 1.9894 9.0716
ME1 GDSC2 3.8768 9.2077 0.8277 13.9342
⏷ Show the Full List of 162 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACM5.1 C GDSC2 -0.0363 2.3664 -0.1333 34.1712
OACP4 C GDSC2 0.4565 4.9561 -0.3651 32.6563
KYSE-220 GDSC2 0.7256 4.1631 0.2212 28.6473
FLO-1 GDSC2 0.8529 4.3467 0.2916 27.6982
SK-GT-4 GDSC2 1.059 5.0168 0.2471 26.9879
KYSE-50 GDSC2 1.147 4.4705 0.5593 24.971
KYAE-1 GDSC2 1.2313 4.2174 0.7457 23.5909
HCE-4 GDSC2 1.3738 3.9347 1.0018 21.5521
TE-12 GDSC2 1.4584 4.3108 0.9529 21.4569
ESO-51 GDSC2 1.4658 4.7204 0.7964 22.2992
ESO-26 GDSC2 3.3362 6.7224 1.6336 10.6242
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 1.2056 5.7514 0.0847 27.1525
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC2 -1.1193 2.6349 -1.3561 45.1339
CHP-212 GDSC2 -0.958 3.3084 -1.3452 43.9734
SJNB-10 GDSC2 -0.7836 2.856 -1.0405 42.0615
SK-N-AS GDSC2 -0.5118 4.633 -1.2812 40.9941
NB(TU)1 GDSC2 -0.053 2.5661 -0.1858 34.5048
SJNB-12 GDSC2 -0.0295 4.1772 -0.6003 36.1106
SJNB-13 GDSC2 -0.0256 4.0536 -0.5545 35.9149
SiMa GDSC2 0.0199 3.4998 -0.3318 34.7634
SK-N-FI GDSC2 0.1036 4.6133 -0.6116 35.4407
SK-N-DZ GDSC2 0.1849 3.178 -0.0634 32.6924
Kelly GDSC2 0.1915 4.3536 -0.4229 34.2374
MHH-NB-11 GDSC2 0.3474 2.0396 0.3156 30.01
SJNB-14 GDSC2 0.55 3.1531 0.3413 28.8824
KP-N-YS GDSC2 0.5825 3.3114 0.3352 28.7558
CHP-134 GDSC2 0.7598 3.2902 0.5344 26.8789
IMR-5 GDSC2 0.7864 2.4013 0.7412 25.6741
NB1 GDSC2 0.8521 3.5561 0.5591 26.3145
TGW GDSC2 0.8864 2.1427 0.8704 24.5217
SK-N-BE(2)-M17 GDSC2 1.0477 3.3275 0.8385 23.9186
NH-12 GDSC2 1.0831 6.8475 -0.5336 30.4594
SJNB-6 GDSC2 1.2219 5.3418 0.28 26.1058
SJNB-5 GDSC2 1.2372 3.8578 0.8807 22.8261
SK-N-MC-IXC GDSC2 1.247 1.9161 1.2463 20.8257
GOTO GDSC2 1.2553 4.4061 0.6996 23.7371
GI-ME-N GDSC2 1.3662 6.1487 0.0696 26.5423
SK-N-SH GDSC2 1.4231 7.1874 -0.3554 28.2739
SJNB-17 GDSC2 1.9186 4.3693 1.4167 16.8763
SJNB-7 GDSC2 2.6198 7.3596 0.6918 18.5197
KP-N-YN GDSC2 2.8762 7.506 0.8478 16.7815
KP-N-RT-BM-1 GDSC2 3.4318 5.8771 2.1347 7.202
LA-N-6 GDSC2 3.5018 7.0111 1.625 10.2047
CHP-126 GDSC2 3.9782 8.0702 1.47 9.8879
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 0.4955 4.9066 -0.3041 32.2053
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC2 -0.2118 4.5081 -0.913 38.212
MDA-MB-175-VII GDSC2 0.1653 4.3663 -0.4556 34.5067
Hs 578T GDSC2 0.1838 4.8254 -0.6051 34.9963
HDQ-P1 GDSC2 0.2015 5.1644 -0.718 35.3246
MDA-MB-361 GDSC2 0.2054 2.5723 0.0922 31.8387
Evsa-T GDSC2 0.3217 3.5008 -0.0029 31.7101
AU565 GDSC2 0.3612 5.8302 -0.8222 34.8936
CAL-51 GDSC2 0.4953 3.4496 0.2013 29.8546
MRK-nu-1 GDSC2 0.536 1.9921 0.5165 28.0554
MDA-MB-330 GDSC2 0.5833 3.3268 0.3319 28.7689
HCC1599 GDSC2 0.6547 2.2182 0.6219 26.9324
T-47D GDSC2 0.6596 4.2683 0.1124 29.4982
HCC1395 GDSC2 0.6746 5.1139 -0.197 30.8728
EFM-19 GDSC2 0.6878 4.9876 -0.1323 30.5181
DU4475 GDSC2 0.7364 2.3616 0.6928 26.1678
CAL-148 GDSC2 0.7497 2.5932 0.6749 26.1948
OCUB-M GDSC2 0.7828 2.0044 0.7713 25.5385
MDA-MB-453 GDSC2 0.8516 5.5099 -0.1761 29.9539
BT-20 GDSC2 0.8657 2.6105 0.7968 25.0011
COLO 824 GDSC2 0.8828 4.7914 0.1525 28.2567
HCC1954 GDSC2 0.9263 3.6401 0.6142 25.6778
MCF-7 GDSC2 0.9406 5.0509 0.1087 28.2083
EFM-192A GDSC2 0.9612 5.6508 -0.1227 29.2128
YMB-1-E GDSC2 1.1019 4.0827 0.6558 24.6548
JIMT-1 GDSC2 1.1192 4.1647 0.6448 24.6362
HCC70 GDSC2 1.1282 3.7098 0.8117 23.6929
CAL-120 GDSC2 1.1487 4.676 0.4802 25.3848
HCC1806 GDSC2 1.1841 7.5794 -0.7739 30.9795
HCC1143 GDSC2 1.1964 6.1496 -0.1022 28.0831
UACC-893 GDSC2 1.2374 2.7679 1.1708 21.2607
MDA-MB-468 GDSC2 1.2962 3.4129 1.0857 21.4397
BT-549 GDSC2 1.3637 5.7061 0.2662 25.5707
MDA-MB-415 GDSC2 1.4742 3.1928 1.3392 19.2485
CAMA-1 GDSC2 1.4929 3.5339 1.2642 19.5713
CAL-85-1 GDSC2 1.5881 5.1235 0.7526 22.033
MDA-MB-231 GDSC2 1.5935 4.9841 0.8184 21.643
MDA-MB-157 GDSC2 1.6651 4.793 0.9743 20.4675
HCC2218 GDSC2 1.857 6.23 0.5197 22.2398
MFM-223 GDSC2 1.906 5.2756 1.0093 19.2986
HCC1569 GDSC2 2.1925 5.7346 1.0811 17.7859
UACC-812 GDSC2 2.2227 7.2401 0.3854 21.5889
HCC1187 GDSC2 2.4863 5.8091 1.328 15.2481
HCC38 GDSC2 2.6089 9.229 -0.245 23.3753
BT-474 GDSC2 3.0126 9.3347 0.0541 20.6176
MDA-MB-436 GDSC2 3.0686 6.5879 1.4733 12.4252
HCC1419 GDSC2 3.0824 8.1352 0.7129 16.8951
ZR-75-30 GDSC2 3.5207 11.0468 -0.3761 21.1181
BT-483 GDSC2 3.6603 12.4626 -0.9696 23.2446
HCC1937 GDSC2 3.9281 11.9124 -0.4792 20.4256
HCC1428 GDSC2 4.373 10.978 0.3307 15.3314
HCC1500 GDSC2 4.4761 9.5893 1.0903 10.9109
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med GDSC2 -0.6766 1.7125 -0.7303 40.3531
8-MG-BA GDSC2 0.3209 4.0859 -0.1896 32.5743
PFSK-1 GDSC2 0.3813 5.5075 -0.6667 34.2279
SF539 GDSC2 0.388 3.6746 0.0172 31.2819
A-172 GDSC2 0.5008 2.7654 0.3753 28.949
SK-MG-1 GDSC2 0.5421 4.9014 -0.2526 31.7543
D-336MG GDSC2 0.6056 4.0049 0.1464 29.59
Daoy GDSC2 0.6365 1.7231 0.6322 26.9702
H4 GDSC2 0.6752 2.1185 0.6522 26.6762
MOG-G-CCM GDSC2 0.6767 5.3124 -0.2761 31.2121
YH-13 GDSC2 0.6961 2.8241 0.5753 26.9705
MOG-G-UVW GDSC2 0.7169 2.4386 0.6625 26.4188
GI-1 GDSC2 0.7254 3.6922 0.3792 27.8469
Becker GDSC2 0.7498 3.6622 0.4151 27.5466
Hs 683 GDSC2 0.874 2.3692 0.8377 24.7498
42-MG-BA GDSC2 0.9016 4.3306 0.3499 27.176
SW1783 GDSC2 0.9102 3.1645 0.7312 25.1323
D-542MG GDSC2 0.916 2.6015 0.852 24.4711
LN-18 GDSC2 0.9262 2.3571 0.8941 24.2046
AM-38 GDSC2 0.9268 3.2498 0.7274 25.0743
SW1088 GDSC2 0.9879 4.0921 0.5295 25.8439
D-392MG GDSC2 1.0573 4.1122 0.5971 25.1705
GaMG GDSC2 1.1008 2.6473 1.0433 22.5835
D-423MG GDSC2 1.118 3.0606 0.9827 22.8199
D-566MG GDSC2 1.1937 2.4255 1.169 21.4823
U-87MG ATCC GDSC2 1.2469 5.9892 0.021 27.2834
U-118MG GDSC2 1.3339 5.6269 0.2708 25.6732
GB-1 GDSC2 1.3575 6.5146 -0.1067 27.4212
D-263MG GDSC2 1.3853 3.726 1.0857 21.0369
T98G GDSC2 1.389 4.1084 0.9554 21.7438
SF126 GDSC2 1.4388 4.8683 0.7067 22.9098
M059J GDSC2 1.4552 3.7087 1.1674 20.2739
D-247MG GDSC2 1.4673 3.74 1.1701 20.2051
KS-1 [Human Krukenberg tumour] GDSC2 1.5837 5.1104 0.7537 22.0446
SF295 GDSC2 1.6026 3.3511 1.4375 18.1247
YKG-1 GDSC2 1.6647 4.1 1.2541 18.8745
SNB-75 GDSC2 1.6821 3.921 1.3392 18.318
SF268 GDSC2 1.7039 5.2618 0.8104 21.2372
KALS-1 GDSC2 1.7682 4.8416 1.0604 19.5533
D-502MG GDSC2 1.8004 4.7721 1.1237 19.0579
CAS-1 GDSC2 1.8145 4.9151 1.0763 19.2747
U-251MG GDSC2 1.8569 5.7215 0.7564 20.9337
KINGS-1 GDSC2 1.9437 6.6285 0.4153 22.4672
DBTRG-05MG GDSC2 2.2326 6.8805 0.5695 20.5588
DK-MG GDSC2 2.2926 7.0233 0.5563 20.4142
ONS-76 GDSC2 2.4301 6.2677 1.0528 17.092
LN-229 GDSC2 2.4445 6.2506 1.0747 16.9115
Onda 10 GDSC2 3.0333 5.7339 1.8677 10.0775
KNS-81-FD GDSC2 3.0701 5.8442 1.8452 10.1027
LN-405 GDSC2 3.1657 6.2484 1.7266 10.5514
D-245MG GDSC2 3.3594 6.3123 1.8578 9.1535
KNS-42 GDSC2 3.3919 6.6789 1.7014 10.0405
Onda 11 GDSC2 3.4581 6.0526 2.0684 7.5476
NMC-G1 GDSC2 3.5781 5.6759 2.351 5.4417
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC2 -0.6017 2.5014 -0.7672 40.0332
ETK-1 GDSC2 0.4176 4.1224 -0.0975 31.6715
TGBC1TKB GDSC2 2.0778 5.8148 0.9312 19.0891
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA GDSC2 0.0261 3.146 -0.2285 34.279
ESS-1 GDSC2 0.4045 2.4274 0.3301 29.6531
KLE GDSC2 1.3541 8.7919 -1.1869 31.7774
EN GDSC2 1.4769 6.3276 0.0984 25.9413
MFE-319 GDSC2 1.4818 3.8199 1.1587 20.2042
RL95-2 GDSC2 1.6231 5.5181 0.6139 22.6554
MFE-280 GDSC2 1.7814 6.9555 0.1029 24.7001
MFE-296 GDSC2 3.1116 8.2928 0.6591 17.1063
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-909 GDSC2 -0.8297 3.3103 -1.2057 42.7973
CAL-54 GDSC2 -0.4805 4.1068 -1.0659 40.2334
LB996-RCC GDSC2 0.3013 3.6507 -0.0699 32.1277
SW13 GDSC2 0.3129 2.9247 0.1374 31.0748
A-498 GDSC2 0.3679 8.7795 -2.1384 38.5334
KTCTL-13 GDSC2 0.4962 2.8358 0.356 29.0699
UO-31 GDSC2 1.0743 2.863 0.9773 23.0558
A-704 GDSC2 1.0759 6.5096 -0.3866 29.8758
KTCTL-140 GDSC2 1.1794 2.8162 1.0999 21.9098
ACHN GDSC2 1.1932 3.9857 0.7889 23.5246
KTCTL-1M GDSC2 1.2032 4.2627 0.6987 23.9713
NCC021 GDSC2 1.2154 4.1895 0.739 23.6979
KTCTL-26A GDSC2 1.2963 3.3077 1.1152 21.2794
769-P GDSC2 1.3052 3.6699 1.0171 21.7735
786-O GDSC2 1.3258 6.0217 0.0863 26.6308
KTCTL-21 GDSC2 1.407 3.5013 1.1805 20.4182
Caki-1 GDSC2 1.4129 4.1004 0.9841 21.4797
RCC10RGB GDSC2 1.4535 7.2724 -0.3658 28.1952
LB2241-RCC GDSC2 1.4542 3.3306 1.2813 19.6535
NCC010 GDSC2 1.489 4.3197 0.9821 21.1621
KTCTL-195 GDSC2 1.5043 4.5619 0.9019 21.547
HA7-RCC GDSC2 1.578 3.9737 1.208 19.5081
LB1047-RCC GDSC2 1.5953 3.9586 1.2321 19.2969
KMRC-20 GDSC2 1.599 8.2134 -0.6749 28.9103
KMRC-1 GDSC2 1.6652 4.3592 1.1536 19.4445
TK-10 GDSC2 1.9457 5.5369 0.93 19.6008
SN12C GDSC2 2.0552 6.6928 0.4918 21.636
BB65-RCC GDSC2 2.6347 5.2569 1.7355 12.2339
RXF 393L GDSC2 2.8629 5.4277 1.8657 10.6443
OS-RC-2 GDSC2 3.0813 9.9931 -0.2162 21.7082
SW156 GDSC2 3.5018 6.6551 1.8027 9.0962
VMRC-RCZ GDSC2 3.9841 11.8668 -0.412 19.9699
VMRC-RCW GDSC2 4.0644 6.9378 2.0892 5.8893
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320HSR GDSC2 -0.2896 2.3543 -0.4037 36.7669
LoVo GDSC2 0.1703 3.7332 -0.2381 33.5629
SK-CO-1 GDSC2 0.1825 3.4873 -0.1507 33.1081
SW48 GDSC2 0.188 3.4396 -0.1311 32.9905
HCT 116 GDSC2 0.2949 3.2853 0.0284 31.6958
C2BBe1 GDSC2 0.4031 3.5643 0.0671 30.9674
COLO205 GDSC2 0.4744 4.0735 -0.0192 31.0258
HCT 15 GDSC2 0.491 3.5302 0.1731 30.0156
GP5d GDSC2 0.562 4.8488 -0.2108 31.4738
NCI-H747 GDSC2 0.6013 5.5362 -0.4481 32.2981
KM12 GDSC2 0.6155 3.8786 0.1995 29.2802
DiFi GDSC2 0.6332 3.139 0.4355 27.9968
SNU-175 GDSC2 0.6736 2.4294 0.6175 26.862
MDST8 GDSC2 0.6887 2.8807 0.5555 27.1089
SNU-C5 GDSC2 0.6958 7.6321 -1.281 34.8438
SW948 GDSC2 0.7465 5.9341 -0.467 31.6932
HT115 GDSC2 0.9042 3.1255 0.7344 25.1441
SNU-407 GDSC2 0.9813 4.2122 0.479 26.1405
NCI-H508 GDSC2 1.1516 3.4884 0.9059 23.0767
HCC2998 GDSC2 1.184 4.2358 0.6881 24.1137
RKO GDSC2 1.1917 3.8592 0.831 23.3015
CCK-81 GDSC2 1.2254 4.932 0.4568 25.1725
CaR-1 GDSC2 1.2558 3.434 1.0355 21.8971
CW-2 GDSC2 1.2996 6.5989 -0.2033 28.1087
SW620 GDSC2 1.4047 4.5988 0.7818 22.64
SNU-283 GDSC2 1.4099 3.5173 1.1788 20.4144
LS411N GDSC2 1.4322 7.1472 -0.3276 28.1146
HT-29 GDSC2 1.4724 4.7931 0.7732 22.4002
LS123 GDSC2 1.5098 6.9517 -0.1597 27.0398
LS180 GDSC2 1.517 4.4397 0.9645 21.1421
T84 GDSC2 1.6167 4.8719 0.8905 21.1415
SNU-C1 GDSC2 1.8578 5.7575 0.7407 21.0182
HT-55 GDSC2 1.8768 5.6721 0.7991 20.6151
CL-11 GDSC2 1.884 6.8902 0.2329 23.648
NCI-H716 GDSC2 1.9542 5.5298 0.9417 19.5002
SNU-C2B GDSC2 2.1447 5.4768 1.1552 17.5281
SNU-81 GDSC2 2.3839 5.7772 1.2458 16.1081
SW837 GDSC2 2.716 7.587 0.6655 18.3436
SNU-61 GDSC2 3.1174 8.5401 0.5405 17.7441
SW1463 GDSC2 3.2317 9.1622 0.3263 18.5415
SW1417 GDSC2 3.2825 9.9091 -0.0045 20.0704
LS1034 GDSC2 3.3987 7.3794 1.3568 12.1499
SW626 GDSC2 3.4009 7.6937 1.2015 13.0832
SW1116 GDSC2 3.5297 9.4703 0.4191 17.1611
RCM-1 [Human ESC] GDSC2 5.0461 14.1816 -0.7466 18.724
COLO 678 GDSC2 5.0709 14.4313 -0.8511 19.1013
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 3.5017 6.4441 1.908 8.4362
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-387 GDSC2 0.37 3.73 -0.0196 31.5463
HLE GDSC2 1.1658 4.0843 0.724 23.9998
SNU-398 GDSC2 1.1686 4.3754 0.6189 24.556
Hep 3B2.1-7 GDSC2 1.1768 4.0729 0.7401 23.8634
HuH-1 GDSC2 1.2528 6.5478 -0.2264 28.4111
JHH-2 GDSC2 1.2758 4.5321 0.6721 23.7973
SK-HEP-1 GDSC2 1.3592 4.8793 0.6188 23.7277
JHH-1 GDSC2 1.433 6.149 0.1366 25.9338
SNU-423 GDSC2 1.5689 5.3979 0.6123 22.8862
JHH-6 GDSC2 2.1275 10.5915 -1.3506 29.4742
SNU-449 GDSC2 2.1864 4.6111 1.5914 14.7746
JHH-7 GDSC2 2.2014 7.6505 0.1651 22.809
Hep-G2/C3A GDSC2 2.4111 5.1796 1.5563 14.1337
JHH-4 GDSC2 2.5312 7.5483 0.5183 19.7837
Huh-7 GDSC2 2.8716 9.5583 -0.179 22.1999
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 182 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EPLC-272H GDSC2 -0.6935 3.9291 -1.2399 42.0013
NCI-H1648 GDSC2 -0.6302 2.1159 -0.7318 40.0784
NCI-H446 GDSC2 -0.2714 1.9656 -0.3295 36.3356
NCI-H1975 GDSC2 -0.2053 5.3959 -1.2412 39.1486
NCI-H524 GDSC2 -0.1402 2.3474 -0.2419 35.2283
NCI-H847 GDSC2 -0.0962 2.261 -0.1814 34.7129
NCI-H2170 GDSC2 -0.0729 4.6202 -0.804 37.0811
IST-SL1 GDSC2 0.0323 2.515 -0.0844 33.5813
NCI-H69 GDSC2 0.0452 2.8946 -0.1471 33.8087
HCC78 GDSC2 0.0486 4.8408 -0.7556 36.2582
NCI-H292 GDSC2 0.0998 3.2546 -0.1764 33.6558
NCI-H1703 GDSC2 0.1169 2.5983 -0.0081 32.779
NCI-H1793 GDSC2 0.1262 6.4076 -1.3122 37.6164
NCI-H2795 GDSC2 0.1267 4.0598 -0.3913 34.4462
NCI-H1876 GDSC2 0.1323 2.9903 -0.0744 33.0151
IST-SL2 GDSC2 0.1376 3.3835 -0.1703 33.4304
NCI-H2171 GDSC2 0.1627 1.824 0.1399 31.8175
HCC44 GDSC2 0.2534 2.8444 0.0904 31.6049
SBC-5 GDSC2 0.2768 3.0528 0.0682 31.595
NCI-H3122 GDSC2 0.3294 4.1647 -0.2075 32.6106
RERF-LC-KJ GDSC2 0.3484 5.5066 -0.7009 34.5188
NCI-H2023 GDSC2 0.3592 5.2767 -0.5959 34.0685
HARA [Human squamous cell lung carcinoma] GDSC2 0.3661 3.1571 0.1396 30.7984
COR-L105 GDSC2 0.3675 4.4575 -0.2708 32.6963
SBC-1 GDSC2 0.4386 2.3799 0.3734 29.2647
DMS 273 GDSC2 0.4964 4.2897 -0.0712 31.1606
NCI-H1048 GDSC2 0.5094 2.4784 0.4349 28.6023
NCI-H2122 GDSC2 0.5165 1.8059 0.5068 28.2016
NCI-H460 GDSC2 0.5462 2.3461 0.4927 28.1261
NCI-H1792 GDSC2 0.5487 3.1487 0.3409 28.891
A-549 GDSC2 0.5587 3.2473 0.3264 28.9163
NCI-H250 GDSC2 0.6013 5.7194 -0.5253 32.6113
UMC-11 GDSC2 0.6289 5.436 -0.3774 31.8728
RERF-LC-Sq1 GDSC2 0.6353 5.2032 -0.2749 31.4034
RERF-LC-MS GDSC2 0.6569 3.3357 0.4098 28.0158
NCI-H1944 GDSC2 0.6826 6.3861 -0.7305 33.0245
NCI-H1666 GDSC2 0.6977 8.8286 -1.8378 36.4084
LB647-SCLC GDSC2 0.7021 2.8639 0.5736 26.9506
NCI-H1755 GDSC2 0.7141 2.8541 0.5887 26.8144
NCI-H835 GDSC2 0.7194 5.2384 -0.2007 30.678
NCI-H322M GDSC2 0.7413 5.0854 -0.1152 30.1883
NCI-H1581 GDSC2 0.787 3.4953 0.5063 26.8971
NCI-H64 GDSC2 0.7871 5.8591 -0.3926 31.1958
EMC-BAC-2 GDSC2 0.7965 3.8186 0.4158 27.323
ChaGo-K-1 GDSC2 0.8072 2.7406 0.7115 25.727
NCI-H2110 GDSC2 0.817 2.6681 0.735 25.5574
CPC-N GDSC2 0.8277 4.4132 0.2398 28.0767
COR-L23 GDSC2 0.838 5.3451 -0.1208 29.765
NCI-H720 GDSC2 0.8465 2.8084 0.7413 25.3822
SHP-77 GDSC2 0.8691 2.9021 0.7469 25.2454
LK-2 GDSC2 0.8752 4.926 0.0906 28.5949
NCI-H1623 GDSC2 0.8827 5.1627 0.0019 28.9869
NCI-H209 GDSC2 0.8839 3.5066 0.6086 25.905
NCI-H82 GDSC2 0.9035 3.5786 0.6084 25.8145
NCI-H1993 GDSC2 0.9043 3.0614 0.7498 25.0627
NCI-H1734 GDSC2 0.9098 2.4916 0.8611 24.4543
NCI-H2009 GDSC2 0.9274 3.8717 0.5403 26.064
SBC-3 GDSC2 0.9307 3.1759 0.7507 24.9325
COR-L279 GDSC2 0.9344 5.6284 -0.1407 29.4163
EMC-BAC-1 GDSC2 0.9474 3.758 0.5996 25.6582
NCI-H1781 GDSC2 0.9734 5.8723 -0.2064 29.5387
NCI-H1155 GDSC2 0.9737 2.1063 0.963 23.6185
LXF 289 GDSC2 0.9759 3.5778 0.6874 25.0591
COR-L311 GDSC2 0.9762 3.3157 0.7637 24.6509
A-427 GDSC2 0.9939 6.4442 -0.4398 30.4607
NCI-H596 GDSC2 1.0036 5.1297 0.1424 27.7586
Calu-6 GDSC2 1.0045 4.4298 0.4228 26.3295
NCI-H1299 GDSC2 1.0128 6.1549 -0.291 29.7391
COR-L303 GDSC2 1.018 3.46 0.7685 24.4308
NCI-H2228 GDSC2 1.0419 5.1407 0.1779 27.4112
NCI-H838 GDSC2 1.0429 3.4853 0.7883 24.2094
LC-2/ad GDSC2 1.0653 3.8374 0.7013 24.5748
HCC33 GDSC2 1.0707 3.6956 0.7538 24.2677
PC-14 GDSC2 1.0788 3.2009 0.9059 23.4127
NCI-H211 GDSC2 1.0834 4.0258 0.6561 24.736
COR-L321 GDSC2 1.0855 2.8153 0.9986 22.8903
EBC-1 GDSC2 1.087 5.4761 0.0826 27.6802
NCI-H2373 GDSC2 1.1096 6.1867 -0.2069 28.9392
NCI-H526 GDSC2 1.1193 6.2115 -0.2081 28.9022
LCLC-103H GDSC2 1.1421 6.3098 -0.2293 28.8987
NCI-H1437 GDSC2 1.1491 2.8745 1.0561 22.285
Lu-65 GDSC2 1.1502 3.0302 1.0247 22.4456
LCLC-97TM1 GDSC2 1.1912 5.1139 0.3451 25.9045
NCI-H1770 GDSC2 1.2072 3.6318 0.9226 22.7323
NCI-H1963 GDSC2 1.2107 5.213 0.3234 25.9315
NCI-H510A GDSC2 1.2206 2.1312 1.2154 21.113
NCI-H1436 GDSC2 1.2313 2.4092 1.21 21.0874
NCI-H1355 GDSC2 1.2519 4.8514 0.5178 24.7332
HCC15 GDSC2 1.2536 6.4857 -0.1972 28.2754
LOU-NH91 GDSC2 1.2608 4.8442 0.5303 24.6281
DMS 114 GDSC2 1.266 5.1627 0.4023 25.2826
NCI-H841 GDSC2 1.2675 3.9979 0.8647 22.7793
NCI-H23 GDSC2 1.2713 4.0164 0.8622 22.776
CAL-12T GDSC2 1.294 4.4979 0.7049 23.5394
Lu-135 GDSC2 1.2953 4.3113 0.7788 23.1292
Ms-1 GDSC2 1.3105 3.5942 1.0468 21.5869
Lu-99A GDSC2 1.3603 5.44 0.3802 24.996
NCI-H2369 GDSC2 1.3721 5.1472 0.5191 24.2112
NCI-H520 GDSC2 1.3924 4.8682 0.6582 23.3719
NCI-H2081 GDSC2 1.4067 4.5718 0.7948 22.5593
HOP-62 GDSC2 1.4589 5.2323 0.5721 23.5599
COR-L32 GDSC2 1.4917 4.0151 1.1001 20.4881
NCI-H1651 GDSC2 1.5207 3.7091 1.2383 19.5899
PaCa-3 GDSC2 1.5326 5.0431 0.73 22.3878
NCI-H1563 GDSC2 1.5356 7.827 -0.55 28.6497
LC-1/sq GDSC2 1.5909 6.5369 0.1144 25.398
NCI-H647 GDSC2 1.5928 4.3854 1.0664 20.2449
NCI-H1573 GDSC2 1.5969 5.9718 0.3818 24.0078
NCI-H2196 GDSC2 1.6289 4.5964 1.0189 20.3636
NCI-H748 GDSC2 1.6321 4.1291 1.2082 19.2741
NCI-H2731 GDSC2 1.6598 4.6762 1.018 20.2406
NCI-H2818 GDSC2 1.683 6.9479 0.0111 25.5364
VMRC-LCD GDSC2 1.6949 4.2678 1.2214 18.9324
NCI-H2810 GDSC2 1.7142 4.7739 1.0335 19.9278
NCI-H2030 GDSC2 1.757 3.8318 1.452 17.3563
BEN GDSC2 1.8482 5.1201 1.0204 19.4625
NCI-H358 GDSC2 1.8553 5.8049 0.7163 21.1646
HCC827 GDSC2 1.9411 5.8145 0.7968 20.3789
NCI-H2141 GDSC2 1.9721 7.4225 0.061 24.177
Lu-134-A GDSC2 2.003 4.5358 1.4348 16.4278
NCI-H2227 GDSC2 2.0382 4.2911 1.5744 15.468
HCC366 GDSC2 2.1506 4.8946 1.4285 15.8831
NCI-H146 GDSC2 2.1509 5.0487 1.3589 16.296
KNS-62 GDSC2 2.1685 5.6274 1.1081 17.7164
NCI-H1915 GDSC2 2.1701 8.933 -0.4931 26.0118
NCI-H2461 GDSC2 2.1947 8.0646 -0.0438 23.8673
Calu-3 GDSC2 2.2238 5.8116 1.075 17.7056
NCI-H1693 GDSC2 2.2251 6.5762 0.7098 19.8058
NCI-H1694 GDSC2 2.2319 6.6994 0.6566 20.0786
NCI-H522 GDSC2 2.2491 8.8412 -0.3759 25.2152
NCI-H2087 GDSC2 2.2809 6.2537 0.9184 18.412
SK-MES-1 GDSC2 2.2893 6.8726 0.6266 20.0382
NCI-H2066 GDSC2 2.3356 7.1752 0.5222 20.4471
NCI-H650 GDSC2 2.407 7.5851 0.3869 20.9229
NCI-H290 GDSC2 2.4324 5.2885 1.5256 14.2422
NCI-H1092 GDSC2 2.4336 10.3474 -0.956 26.9873
NCI-H661 GDSC2 2.4689 7.523 0.4741 20.2389
NCI-H2803 GDSC2 2.5417 4.7915 1.8666 11.7642
NCI-H441 GDSC2 2.5658 9.27 -0.3035 23.7902
NCI-H2722 GDSC2 2.5661 7.6448 0.5023 19.751
NCI-H513 GDSC2 2.5948 8.4251 0.1416 21.5482
NCI-H2804 GDSC2 2.6453 6.3435 1.2159 15.3735
NCI-H727 GDSC2 2.764 6.5621 1.2162 14.9732
HOP-92 GDSC2 2.7925 7.7497 0.6527 18.1619
NCI-H2085 GDSC2 2.8133 5.1729 1.9446 10.3199
COLO 668 GDSC2 2.8217 6.1189 1.4875 13.1285
SW1271 GDSC2 2.8505 7.7968 0.6805 17.8167
EKVX GDSC2 2.901 5.1995 2.0129 9.5978
NCI-H1568 GDSC2 2.9636 10.7279 -0.6837 24.1574
NCI-H2347 GDSC2 2.9859 8.3094 0.5429 18.1443
SK-LU-1 GDSC2 3.0583 7.5856 0.9666 15.5113
NCI-H2291 GDSC2 3.0675 6.0113 1.7597 10.6471
SW1573 GDSC2 3.1368 10.0964 -0.2208 21.5568
NCI-H1341 GDSC2 3.1797 7.7381 0.9943 14.9741
ABC-1 GDSC2 3.1975 6.1223 1.8168 9.8896
NCI-H3255 GDSC2 3.2701 6.4369 1.721 10.273
NCI-H810 GDSC2 3.2841 6.1581 1.8722 9.2826
NCI-H2869 GDSC2 3.3417 6.8804 1.5592 11.0704
NCI-H2029 GDSC2 3.3529 5.0407 2.4882 5.189
NCI-H1650 GDSC2 3.361 9.3112 0.3598 17.9737
NCI-H2172 GDSC2 3.4149 5.5667 2.276 6.3562
NCI-H226 GDSC2 3.4168 8.1241 0.9994 14.236
NCI-H2595 GDSC2 3.4424 8.8956 0.6348 16.2422
NCI-H345 GDSC2 3.4463 5.156 2.5064 4.8131
NCI-H2405 GDSC2 3.5058 7.7081 1.2801 12.3084
NCI-H196 GDSC2 3.536 9.921 0.1991 18.2936
DMS 79 GDSC2 3.6828 5.9046 2.3176 5.3832
NCI-H1836 GDSC2 3.6837 7.6516 1.4507 10.7772
NCI-H2591 GDSC2 3.7385 12.2939 -0.8218 22.4239
NCI-H1869 GDSC2 3.7936 12.6677 -0.964 22.847
IA-LM GDSC2 3.8092 10.0209 0.3694 16.63
Lu-165 GDSC2 3.9138 7.2168 1.8431 7.7636
NCI-H1838 GDSC2 4.0145 6.7549 2.1428 5.6739
NCI-H2444 GDSC2 4.053 6.1514 2.4603 3.6599
NCI-H740 GDSC2 4.1391 7.3911 1.9216 6.7433
NCI-H1105 GDSC2 4.1487 7.5147 1.8683 7.047
NCI-H2342 GDSC2 4.1706 10.1673 0.5783 14.539
NCI-H2135 GDSC2 4.2461 8.4714 1.4709 9.2237
NCI-H1688 GDSC2 4.2924 10.5553 0.4788 14.759
COR-L88 GDSC2 4.4792 8.8054 1.4745 8.6608
DMS 53 GDSC2 4.4953 13.3413 -0.7466 20.0803
NCI-H1435 GDSC2 4.5417 11.8277 0.0378 16.3834
⏷ Show the Full List of 182 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 1.4686 3.9777 1.0887 20.653
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-6 GDSC2 -0.0133 5.034 -0.8955 37.0669
TE-11 GDSC2 0.4391 2.978 0.2626 29.8236
KYSE-150 GDSC2 0.5714 4.1359 0.0642 30.1554
OE21 GDSC2 0.5825 5.411 -0.4157 32.2543
EC-GI-10 GDSC2 0.6048 3.5173 0.301 28.8221
OE19 GDSC2 0.7016 5.0634 -0.1482 30.5251
TE-4 GDSC2 0.9542 2.2229 0.9354 23.8554
KYSE-510 GDSC2 1.0293 2.5186 0.9848 23.2337
T.T GDSC2 1.0891 2.9911 0.9668 23.0408
TE-10 GDSC2 1.2107 3.2714 1.0314 22.1267
KYSE-180 GDSC2 1.2262 4.0856 0.7887 23.379
OE33 GDSC2 1.2627 5.186 0.389 25.367
TE-5 GDSC2 1.3037 3.5641 1.0488 21.6067
KYSE-520 GDSC2 1.3181 4.9628 0.5409 24.3242
TE-1 GDSC2 1.3574 5.3663 0.4093 24.8558
TE-9 GDSC2 1.439 4.2593 0.9522 21.5443
KYSE-450 GDSC2 1.4474 3.942 1.0787 20.8012
KYSE-270 GDSC2 1.458 4.7108 0.7922 22.3557
KYSE-140 GDSC2 1.4703 5.6717 0.39 24.4841
KYSE-410 GDSC2 1.5337 4.8278 0.8228 21.867
TE-8 GDSC2 1.5769 4.9778 0.8039 21.7927
KYSE-70 GDSC2 1.9866 5.3698 1.0475 18.7633
COLO 680N GDSC2 4.5564 10.5469 0.6795 13.0192
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IGROV-1 GDSC2 -1.8247 3.5573 -2.3608 51.266
A2780 GDSC2 -1.0596 3.0242 -1.3819 44.7533
JHOS-4 GDSC2 0.1388 2.5024 0.0327 32.4687
TOV-112D GDSC2 0.2174 3.0069 0.0144 32.1558
TYK-nu GDSC2 0.5748 5.5017 -0.4614 32.4799
OVCAR-8 GDSC2 0.9838 5.3528 0.028 28.4037
OVISE GDSC2 0.9878 5.3495 0.0337 28.358
OC 314 GDSC2 0.9991 3.2959 0.794 24.3824
OVTOKO GDSC2 1.1024 6.4069 -0.3133 29.4435
OAW42 GDSC2 1.2005 5.8356 0.0422 27.3804
OVCAR-5 GDSC2 1.2548 5.8618 0.086 26.9344
RMG-I GDSC2 1.2951 5.1823 0.4242 25.0425
OAW28 GDSC2 1.3973 7.1537 -0.3649 28.4212
OVCAR-3 GDSC2 1.4756 4.7875 0.7789 22.3555
Caov-3 GDSC2 1.4936 4.1566 1.0495 20.7639
JHOS-2 GDSC2 1.506 3.9766 1.1295 20.2617
OVK18 GDSC2 1.5194 3.3644 1.343 19.0198
DOV13 GDSC2 1.5811 4.0585 1.1801 19.6515
ES-2 GDSC2 1.6245 4.8096 0.9251 20.914
Caov-4 GDSC2 1.7681 7.5212 -0.1806 26.112
EFO-21 GDSC2 2.0868 7.2266 0.2643 22.7214
SK-OV-3 GDSC2 2.2274 5.7734 1.0966 17.5656
OVCAR-4 GDSC2 2.6563 9.9853 -0.5795 24.7083
FU-OV-1 GDSC2 2.7817 9.1737 -0.0655 21.95
TOV-21G GDSC2 2.9162 5.868 1.6968 11.5224
OV-90 GDSC2 2.9522 6.6028 1.364 13.4632
OV56 GDSC2 3.1459 5.6393 2.0135 8.8084
OVKATE GDSC2 3.4966 8.7852 0.7344 15.527
EFO-27 GDSC2 3.5678 6.9021 1.7324 9.3532
Kuramochi GDSC2 4.745 12.2413 -0.0145 16.1355
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DAN-G GDSC2 0.2485 3.3607 -0.0429 32.2702
PL4 GDSC2 0.5019 3.4644 0.2043 29.8076
PaTu 8902 GDSC2 0.7976 4.4574 0.1909 28.4606
KP-4 GDSC2 0.9825 3.3121 0.7716 24.5793
PaTu 8988t GDSC2 1.1048 7.2181 -0.6832 30.9648
Panc 03.27 GDSC2 1.2133 5.9045 0.0247 27.4101
BxPC-3 GDSC2 1.3941 6.7528 -0.1806 27.6102
MIA PaCa-2 GDSC2 1.4115 6.4713 -0.0329 26.8481
PSN1 GDSC2 1.5131 4.7628 0.8285 21.921
HPAC GDSC2 1.5422 5.71 0.4457 23.8932
HPAF-II GDSC2 1.5842 6.2537 0.2393 24.7967
KP-2 GDSC2 1.6225 5.0904 0.8023 21.6142
Capan-1 GDSC2 1.7009 6.9514 0.0268 25.3898
Hs 766T GDSC2 1.7056 6.5051 0.2421 24.2966
KP-1N GDSC2 1.8071 5.7603 0.6888 21.5067
CFPAC-1 GDSC2 1.8412 6.2494 0.4951 22.4347
Panc 02.03 GDSC2 1.9939 5.9052 0.8065 20.1217
Panc 10.05 GDSC2 2.2659 9.0739 -0.4755 25.5946
HuP-T4 GDSC2 2.3216 8.8533 -0.3161 24.6897
KP-3 GDSC2 2.3835 7.8011 0.2592 21.6761
Panc 08.13 GDSC2 2.4317 8.4365 -0.0105 22.8649
Capan-2 GDSC2 2.4845 7.479 0.51 19.99
HuP-T3 GDSC2 2.5853 7.1446 0.7667 18.2132
YAPC GDSC2 2.5886 8.7408 -0.0205 22.3753
SUIT-2 GDSC2 2.6438 6.0611 1.353 14.5485
QGP-1 GDSC2 3.0568 7.1929 1.1613 14.3617
SW1990 GDSC2 3.2825 6.9345 1.4826 11.7182
SU.86.86 GDSC2 3.2993 7.0247 1.4517 11.859
AsPC-1 GDSC2 3.6762 8.9767 0.7841 14.7335
Panc 04.03 GDSC2 3.6779 12.2445 -0.8463 22.696
MZ-PC-1 GDSC2 4.284 7.3533 2.0408 5.6987
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC2 0.8591 3.4724 0.5916 26.1104
MPP 89 GDSC2 1.8577 8.0846 -0.3677 26.6156
IST-Mes1 GDSC2 2.0667 5.9913 0.8372 19.6702
NCI-H2052 GDSC2 2.11 7.9945 -0.0879 24.3875
MSTO-211H GDSC2 3.1699 13.5064 -1.8975 27.965
NCI-H28 GDSC2 3.2428 8.2979 0.7677 16.0911
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 0.0309 4.295 -0.5756 35.6905
22Rv1 GDSC2 0.6343 4.8925 -0.1512 30.8585
PC-3 GDSC2 1.6828 6.2749 0.3272 23.9478
VCaP GDSC2 2.495 6.4457 1.0268 17.0175
DU145 GDSC2 3.0073 5.8187 1.8025 10.5691
NCI-H660 GDSC2 3.8146 6.2719 2.2347 5.576
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 3.1917 5.9532 1.8962 9.4078
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LOX-IMVI GDSC2 0.2155 4.7853 -0.556 34.644
WM793 GDSC2 0.3367 5.4713 -0.6987 34.5686
WM35 GDSC2 0.5365 3.2656 0.2973 29.1713
COLO 792 GDSC2 0.5579 5.9583 -0.6723 33.3909
A101D GDSC2 0.5765 3.8389 0.1702 29.6137
RPMI-7951 GDSC2 0.619 3.6579 0.274 28.8903
IGR-1 GDSC2 0.6822 3.8372 0.2856 28.5294
A2058 GDSC2 0.6861 1.6455 0.684 26.4616
SK-MEL-31 GDSC2 0.6916 6.2073 -0.6425 32.6474
A-431 GDSC2 0.7631 2.2489 0.7331 25.8302
G-mel GDSC2 0.7672 2.6975 0.6761 26.1041
SK-MEL-28 GDSC2 0.8424 4.4358 0.247 27.9723
M14 GDSC2 0.9206 5.8761 -0.2624 30.0255
G-361 GDSC2 0.9737 5.565 -0.0728 28.9259
MZ-MEL-2 GDSC2 0.9756 3.4388 0.7285 24.8408
A-375 GDSC2 0.9784 3.4916 0.7161 24.8946
MZ-MEL-7 GDSC2 0.9822 2.9816 0.8528 24.1497
IGR-37 GDSC2 1.0173 4.0495 0.5764 25.4618
HT-144 GDSC2 1.0316 4.8536 0.285 26.9185
A-388 GDSC2 1.0473 3.3324 0.8367 23.9295
CP50-MEL-B GDSC2 1.0976 3.6126 0.8093 23.8454
HMV-II GDSC2 1.1752 4.8991 0.4176 25.5971
CHL-1 GDSC2 1.2588 3.4968 1.0203 21.966
UACC-62 GDSC2 1.3049 4.3832 0.7614 23.1829
SK-MEL-5 GDSC2 1.3209 4.4252 0.762 23.11
DJM-1 GDSC2 1.3627 2.9098 1.2806 20.0847
WM1552C GDSC2 1.5118 3.8121 1.1938 19.8767
COLO 783 GDSC2 1.5372 5.0532 0.7304 22.3667
MeWo GDSC2 1.6181 5.2936 0.7088 22.1535
GAK GDSC2 1.6447 3.7686 1.3526 18.405
Hs 938.T GDSC2 1.6493 4.0619 1.252 18.9523
SK-MEL-3 GDSC2 1.6918 3.9753 1.3298 18.329
SK-MEL-2 GDSC2 1.6984 3.9755 1.3369 18.2602
WM115 GDSC2 1.9346 5.4262 0.9697 19.4154
VMRC-MELG GDSC2 2.0003 5.1649 1.1546 18.0842
Mel JuSo GDSC2 2.0267 6.2318 0.6845 20.6839
IST-MEL1 GDSC2 2.0781 5.0936 1.2653 17.1315
Mel Ho GDSC2 2.0803 4.3528 1.5928 15.1892
LB2518-MEL GDSC2 2.2263 4.5767 1.6474 14.2851
IPC-298 GDSC2 2.2308 5.5679 1.1972 16.9576
WM278 GDSC2 2.3066 10.9771 -1.3816 28.969
SK-MEL-24 GDSC2 2.3707 6.2621 0.9995 17.6163
451Lu GDSC2 2.402 5.0235 1.6205 13.7775
SH-4 GDSC2 2.4171 5.8408 1.2469 15.9824
COLO 800 GDSC2 2.5514 4.9934 1.7811 12.2509
CP66-MEL GDSC2 2.5624 4.7131 1.9236 11.3403
COLO 829 GDSC2 2.5781 9.3267 -0.3209 23.8277
WT2-iPS GDSC2 2.6097 5.2021 1.7379 12.307
Hs 940.T GDSC2 2.7778 5.2689 1.8647 10.9381
COLO 679 GDSC2 3.2796 6.0365 1.9292 8.9368
SK-MEL-30 GDSC2 3.2975 6.5649 1.68 10.4481
MMAc-SF GDSC2 3.365 6.0956 1.9708 8.4264
SK-MEL-1 GDSC2 3.609 7.4673 1.4833 10.7815
RVH-421 GDSC2 3.7376 8.1553 1.2423 11.8919
UACC-257 GDSC2 3.9064 10.7903 0.063 17.9305
LB373-MEL-D GDSC2 4.1322 6.8503 2.1788 5.1914
EquiPSC Line K2 GDSC2 0.9566 3.7178 0.6225 25.4943
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 0.5718 2.0995 0.5457 27.7297
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh41 GDSC2 -0.6185 3.2875 -0.969 40.7961
G-401 GDSC2 -0.4594 3.9691 -0.998 39.9091
KYM-1 GDSC2 -0.0612 2.9383 -0.273 34.9438
EW-8 GDSC2 0.5015 1.8058 0.4913 28.3546
MES-SA GDSC2 0.5963 2.4178 0.5366 27.6557
G-402 GDSC2 0.6054 4.4307 -0.0053 30.3224
Hs 633.T GDSC2 0.8273 2.1116 0.8111 25.1155
VA-ES-BJ GDSC2 0.9081 6.8165 -0.6949 31.8671
STS-0421 GDSC2 1.0051 4.1208 0.5378 25.7217
Rh30 GDSC2 1.0503 5.675 -0.0413 28.4362
RD GDSC2 1.0653 4.5868 0.427 26.0345
SW982 GDSC2 1.2715 2.8709 1.1893 21.0001
HT-1080 GDSC2 1.3139 3.4356 1.0985 21.2892
A-204 GDSC2 1.5101 7.5333 -0.4345 28.2633
SK-LMS-1 GDSC2 1.602 4.5002 1.0299 20.4135
TE 441.T GDSC2 1.7165 3.8293 1.4091 17.7743
SW872 GDSC2 1.868 4.7503 1.203 18.325
GCT GDSC2 2.0222 7.9272 -0.1369 24.9437
MFH-ino GDSC2 2.4389 6.2914 1.0495 17.0802
SK-UT-1 GDSC2 2.6776 7.0167 0.9134 17.0563
SW684 GDSC2 2.8331 5.5993 1.754 11.4396
RKN GDSC2 3.3309 6.5681 1.7063 10.1864
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC2 -0.9746 1.3477 -1.0102 43.2468
Fu97 GDSC2 -0.1699 3.5264 -0.5466 36.6803
23132/87 GDSC2 -0.1672 5.1299 -1.0967 38.5295
NCI-N87 GDSC2 0.0901 5.4752 -0.9602 36.7338
HSC-39 GDSC2 0.1651 1.1942 0.164 31.6844
SNU-16 GDSC2 0.3166 1.7079 0.3057 30.2139
AGS GDSC2 0.3747 2.9159 0.2067 30.4225
RF-48 GDSC2 0.6844 4.0436 0.2185 28.8561
IM95 GDSC2 0.7446 3.0787 0.5717 26.7562
SK-GT-2 GDSC2 0.7473 4.3182 0.1886 28.7079
Hs 746.T GDSC2 0.9535 6.42 -0.4697 30.7648
GCIY GDSC2 0.999 4.2701 0.4769 26.0711
NUGC-3 GDSC2 1.0561 4.4521 0.4694 25.8528
SNU-1 GDSC2 1.0746 2.5694 1.0264 22.7981
MKN45 GDSC2 1.1338 4.7919 0.4178 25.7782
ECC10 GDSC2 1.157 5.2321 0.2595 26.4925
TMK-1 GDSC2 1.2109 2.4807 1.1817 21.333
TGBC11TKB GDSC2 1.2373 4.7023 0.5633 24.5537
MKN1 GDSC2 1.2965 5.3705 0.3447 25.4522
MKN28 GDSC2 1.4436 4.701 0.7811 22.4779
SNU-5 GDSC2 1.5816 4.8073 0.8813 21.3392
SCH GDSC2 1.5846 4.9156 0.8386 21.5665
RERF-GC-1B GDSC2 2.3096 9.3956 -0.5949 25.9529
NUGC-4 GDSC2 2.4065 7.6986 0.3306 21.2224
OCUM-1 GDSC2 2.5262 7.1539 0.7082 18.7472
MKN7 GDSC2 2.5885 6.013 1.3251 14.9084
ECC12 GDSC2 3.2383 5.5211 2.1519 7.6542
KATO III GDSC2 3.4287 9.6548 0.244 18.3778
SNG-M GDSC2 2.2816 4.5001 1.7377 13.5305
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC2 0.4908 2.5576 0.4024 28.8597
FTC-133 GDSC2 0.5764 4.5697 -0.0882 30.8491
8305C GDSC2 0.6031 4.8238 -0.1573 31.0359
IHH-4 GDSC2 0.6395 3.3576 0.3847 28.2283
KMH-2 GDSC2 1.0938 2.5898 1.044 22.6139
B-CPAP GDSC2 1.1222 5.9083 -0.0699 28.254
CAL-62 GDSC2 1.1228 4.4736 0.5323 25.2226
BHT-101 GDSC2 1.2687 6.3851 -0.1361 27.9312
ASH-3 GDSC2 1.3344 4.4215 0.7778 22.9643
HTC-C3 GDSC2 1.3375 5.364 0.3898 25.0428
8505C GDSC2 1.3774 5.8458 0.2177 25.7596
WRO GDSC2 2.4935 6.0438 1.2211 15.8665
ML-1 [Human leukemia] GDSC2 2.7194 6.0585 1.424 13.8594
CGTH-W-1 GDSC2 3.0572 5.6651 1.923 9.6548
TT2609-C02 GDSC2 3.3157 6.419 1.7681 9.8437
TT GDSC2 4.1428 8.4487 1.4063 9.8607
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB49-HNC GDSC2 -1.2634 4.2968 -1.9787 46.9937
DOK GDSC2 -0.418 2.4453 -0.558 38.1421
HO-1-u-1 GDSC2 -0.0496 1.4779 -0.0604 33.8872
BICR 10 GDSC2 0.0624 3.2244 -0.2091 34.0001
HO-1-N-1 GDSC2 0.3372 3.9565 -0.1284 32.216
CAL-27 GDSC2 0.3439 1.5403 0.3393 29.9078
NCI-H3118 GDSC2 0.3696 3.1719 0.1396 30.7805
Detroit 562 GDSC2 0.4228 1.7257 0.4139 29.1376
HSC-3 GDSC2 0.4548 2.7958 0.3193 29.4596
JHU-011 GDSC2 0.4614 2.2993 0.4084 28.9742
HSC-2 GDSC2 0.5667 1.5344 0.565 27.6578
BB30-HNC GDSC2 0.6098 1.8157 0.6021 27.2553
BICR 22 GDSC2 0.683 3.9888 0.2357 28.777
Ca9-22 GDSC2 0.7744 2.9999 0.6226 26.3482
JHU-029 GDSC2 0.8556 2.4982 0.8023 25.0217
CAL-33 GDSC2 0.9746 4.4752 0.3735 26.7211
KOSC-2 GDSC2 0.9842 2.5231 0.9361 23.7046
PCI-15A GDSC2 1.0726 2.4105 1.043 22.7224
KON GDSC2 1.1407 3.0157 1.0176 22.5275
SCC-15 GDSC2 1.1527 4.569 0.5269 25.1191
JHU-022 GDSC2 1.2777 5.4908 0.273 25.9014
OSC-19 GDSC2 1.2979 2.6736 1.2504 20.5543
PCI-06A GDSC2 1.3864 2.988 1.2905 19.9203
FaDu GDSC2 1.4395 3.5598 1.1981 20.175
SAS GDSC2 1.4554 4.1797 1 21.2066
BICR 31 GDSC2 1.4621 3.778 1.1516 20.3309
LB771-HNC GDSC2 1.5181 5.3658 0.5745 23.3009
PCI-04B GDSC2 1.5539 3.8285 1.2337 19.4691
SCC-4 GDSC2 1.7883 5.0036 1.0107 19.7583
SAT [Human HNSCC] GDSC2 2.0501 6.0843 0.7771 20.0751
OSC-20 GDSC2 2.1079 6.3088 0.7262 20.1455
PE/CA-PJ15 GDSC2 2.1112 4.5221 1.5528 15.3004
BICR 78 GDSC2 2.2776 6.4278 0.8313 18.9256
SCC-9 GDSC2 2.3319 6.9294 0.6388 19.818
PCI-30 GDSC2 2.3713 5.7006 1.2703 16.0064
HSC-4 GDSC2 2.4998 8.6574 -0.0585 22.8626
SKN-3 GDSC2 2.9693 6.8079 1.277 13.9387
BHY GDSC2 3.1694 4.9536 2.3757 6.4497
UPCI-SCC-090 GDSC2 3.7061 8.677 0.9574 13.6577
SCC-25 GDSC2 4.7325 6.8683 2.5405 2.0534
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC2 0.3812 2.0215 0.3526 29.6548
HT-1197 GDSC2 0.5273 6.2829 -0.8443 34.1683
CAL-29 GDSC2 0.5294 3.4779 0.2303 29.5434
5637 GDSC2 0.6285 2.9139 0.483 27.7749
KU-19-19 GDSC2 0.6352 4.6237 -0.0458 30.3697
639V GDSC2 1.1074 5.3873 0.1418 27.3002
TCCSUP GDSC2 1.2497 6.2061 -0.0739 27.7226
UM-UC-3 GDSC2 1.3311 3.2472 1.1693 20.8266
647V GDSC2 1.3467 5.361 0.4006 24.947
SW1710 GDSC2 1.3524 5.6159 0.2947 25.4721
RT-112 GDSC2 1.3715 5.004 0.5794 23.8892
SW780 GDSC2 1.5621 6.8912 -0.08 26.4556
RT-4 GDSC2 1.8561 5.3693 0.9166 20.0273
T24 GDSC2 3.0382 4.2204 2.6188 5.352
HT-1376 GDSC2 3.9862 8.5942 1.2168 11.3858
J82 GDSC2 5.3711 12.1682 0.4681 12.2763
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-39 GDSC2 -0.3965 1.9501 -0.4603 37.6087
NCC-IT GDSC2 -0.3679 2.223 -0.4668 37.4771
KGN GDSC2 0.0802 2.6158 -0.0512 33.1751
MS751 GDSC2 0.292 4.2493 -0.2775 33.1075
BPH-1 GDSC2 0.2956 3.6868 -0.0872 32.2369
TC-YIK GDSC2 0.4261 2.6435 0.3177 29.6094
NT2-D1 GDSC2 0.5545 3.1089 0.3571 28.7801
OVCA420 GDSC2 0.7025 5.3074 -0.247 30.9631
JAR GDSC2 0.704 2.0917 0.6843 26.3706
HEY GDSC2 0.8111 3.7792 0.4446 27.1054
ME-180 GDSC2 0.8258 4.1011 0.3514 27.5184
SW954 GDSC2 0.8676 1.9058 0.8624 24.6556
Ca Ski GDSC2 0.8717 3.1854 0.684 25.5636
HeLa GDSC2 0.8836 3.8914 0.4861 26.5513
PA-1 GDSC2 0.8906 3.889 0.4946 26.4745
C-4-I GDSC2 0.9011 2.4835 0.8528 24.5397
PWR-1E GDSC2 0.9482 2.3688 0.9161 23.9833
SiSo GDSC2 1.1377 3.0743 1.001 22.6303
ACC-OV7 GDSC2 1.1654 3.2798 0.9798 22.6138
NEC8 GDSC2 1.1675 2.8542 1.0799 22.0716
OMC-1 [Human cervical carcinoma] GDSC2 1.2999 2.602 1.262 20.4843
SKN GDSC2 1.3223 3.7639 1.0047 21.7649
OVCA433 GDSC2 1.3538 4.5436 0.7502 23.0323
SKG-IIIa GDSC2 1.3641 4.0231 0.9598 21.8281
DSH1 GDSC2 1.3694 5.0414 0.5613 23.9955
C-33 A GDSC2 1.4516 4.012 1.0581 20.898
OVMIU GDSC2 1.6903 5.1671 0.8384 21.1349
LB831-BLC GDSC2 1.8751 6.1812 0.5603 21.9491
UWB1.289 GDSC2 2.2379 5.7399 1.1227 17.3725
JEG-3 GDSC2 2.4512 5.8395 1.2801 15.6616
SiHa GDSC2 2.5875 7.8193 0.4353 20.0405
OV17R GDSC2 2.592 5.8049 1.4297 14.2599
PEO1 GDSC2 2.8172 10.0983 -0.4956 23.8178
JHOS-3 GDSC2 2.841 5.7761 1.6741 11.91
HT-3 GDSC2 2.9045 6.419 1.4131 13.3154
DoTc2 4510 GDSC2 3.1143 6.4468 1.5833 11.6022
HEC-1 GDSC2 3.3403 8.9914 0.5025 17.2708
SW962 GDSC2 3.433 5.3216 2.4131 5.4396
SW756 GDSC2 3.7848 9.9039 0.4083 16.492
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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